Run and gun may refer to:
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Run and gun video game, a sub-genre of shoot 'em up video games
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Run&Gun, a Japanese boy band and performance troupe
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Run and gun (basketball), a style of play in basketball
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Another name for the run and shoot offense, an offensive system in American football
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Run and Gun, a 1993 basketball video game released by Konami in 1993
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Run and Gun II, the 1996 sequel
